TSH inhibits SERCA2a and the PKA/PLN pathway in rat cardiomyocytes
نویسندگان
چکیده
منابع مشابه
TSH inhibits SERCA2a and the PKA/PLN pathway in rat cardiomyocytes
Elevated thyroid-stimulating hormone (TSH) levels often accompany impaired LV diastolic function and subtle systolic dysfunction in subclinical hypothyroidism (sHT). These cardiac dysfunctions are characterized by increases in mean aortic acceleration and pre-ejection/ejection time ratios. To explore the mechanism underlying these pathologies, we investigated the effects of TSH on sarcoplasmic ...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2016
ISSN: 1949-2553
DOI: 10.18632/oncotarget.9393